My '95 Blazer is having issues. She keeps killing the battery, It is NOT the alternator or most of the obvious causes, I have replaced the battery and the alternator a couple of times and keeps draining the battery, I have been unhooking the white wire from the red wire at the alternator and it seems to it from killing the battery, but when the red and white wires are connected it will drain the battery over night. When the red and white wires are touching the battery drains. Any Ideas? This is becoming very frustrating.

You need to do a draw test. Its weird the draw stops when you disconnect the big red wire on the alternator because it should be wired to go directly to the battery. Here is a video on how to do a draw test.