Originally Posted by msandbakken
It only happens while in overdrive and only while accelerating and usually starts around 35mph and when I step on the accelerator it goes up in pitch the the more gas I give it . when I take my Foot off the gas the noise goes away
So that tells me its a transmission problem. When I had that on my car it was the differential, but unlike your car it seemed to happen in all gears. Perhaps we can get SPG358 to chime in on this. He knows more about transmissions than I do. If he doesn't post, send him a PM.