Yes it does. Vacuum leaks can cause all manner of havoc on modern PCM controlled engines. I even went as far as to order the assortment kit of vacuum fittings from NAPA because I've had more than my share of vacuum leaks. One of the leaks I've repaired two or three times is the tee coming off the fuel pressure regulator.
Use the MAF cleaner as was suggested to find the location. I've used WD-40 also, but since it'* not a solvent, it won't evaporate like MAF cleaner so it will have to burn off of the hot engine surfaces.