I have a 2000 SE with enough options to make it almost an SLE. It has about 55,000 miles on it. Haven't had any major problems. I have had a few minor problems over the past few years. (my car is about 5 years old since I purchased it in December of 1999). The rear window motor broke - I think this was the regulator ($350), Some lights went out on radio dispay ($300), control arm ($150), air conditioner drain clogged ($80). I have an extended warranty so this wasn't a big deal. If I had to pay out of my pocket I would not have fixed radio display. Overall, a very reliable solid car. I just bought a 2004 GXP and love it (my wife has my 2000 SE).
I was really amazed that the original brake pads lasted about 40,000 miles and I still have the original battery in the car.
FYI. The coolant seal on the 3.8L engine is covered by a GM recall that is in effect until July 2005.