You should be touching the metal connection inside the boot of the plug wire.
A code like this would send me to check the following. Ohm test the two posts of the coil to ensure one post did not go bad. The average reading is about 5.5 to 7.0 ohms when touching both posts of the same coil.
Checking the wire like you are
Check the plug. Plugs can crack, the end if screw on can come loose etc.
As for the O2, check the wirining to your rear O2 that is the one behind that catalytic converter.
00 Regal GS: All kinds of cool stuff.